Hand, foot and mouth generally refers to hand, foot and mouth disease, which causes a rash that may appear on the legs. Hand, foot and mouth disease mostly occurs in children under 5 years old, manifested by mouth pain, anorexia, low fever, hands, feet, mouth and other parts of the appearance of small herpes or small ulcers, most of the children about a week or so since the cure, there is no specific drug, mainly symptomatic treatment. Hand, foot and mouth disease generally acute onset, fever, mouth pain, anorexia, oral mucosa appear scattered herpes or ulcers, hands, feet, buttocks, arms, legs appeared maculopapular rash, and then turned to herpes, herpes can have inflammatory red halo around, the blisters of liquid less. The appearance of maculopapular rash, herpes with cough and fever on the oral mucosa, hands, feet, buttocks and legs is recommended to go to the pediatric infection department and infectious diseases department of the hospital in time.