The causes of fatigue in a 50-year-old man include excessive fatigue, cardiac insufficiency, liver disease, anemia and so on. 1. overworked: overworked people can appear body aches, memory loss, weakness and other symptoms, overworked to actively rest, if necessary, medical treatment. 2. Cardiac insufficiency: Early cardiac insufficiency only has the symptoms of fatigue or decreased physical strength, and it is mainly to standardize the treatment for the causes of cardiac insufficiency. 3. Liver lesions: Cirrhosis patients will have fatigue and weakness, mainly because of liver function damage, and need to receive systematic treatment. 4. Anemia: mostly pale and bloodless, easy to have a sense of body fatigue, to improve the symptoms, to actively treat anemia. The above are only some of the common causes. If the symptoms of fatigue persist or recur, you should consult a doctor in time. After a clear diagnosis, follow the doctor’s instructions to standardize the treatment.