Nephrotic syndrome and nephritis are two diseases in nephrology, and there is no direct comparison between them as to who is more serious. Nephritis can be mild or severe, while Nephrotic Syndrome has easy and not easy to treat types. 1. Nephritis: In addition to causing facial swelling, elevated blood pressure, and abnormal renal function, symptoms of hematuria tend to be more common, and proteinuria is usually not much. Most acute glomerulonephritis and cryptoglomerulonephritis are usually not serious, and patients have a better prognosis; chronic glomerulonephritis is more serious if it develops in the direction of chronic renal failure uremia. 2. Nephrotic syndrome: it will cause symptoms such as facial edema, elevated blood pressure and abnormal renal function, etc. Generally, there is not much urinary occult blood, proteinuria is more common, and the presence of a large amount of proteinuria will also cause hypoproteinemia. The microscopic lesion type is usually not serious; membranous nephropathy and membranoproliferative glomerulonephritis are prone to develop in the direction of chronic renal insufficiency or renal failure, which is more serious. Whether it is nephritis or nephropathy, all of them are harmful, so it is recommended that patients go to the hospital in time and actively undergo examination and treatment.