Yellow clots in cough sputum are caused by sticky and dry sputum, mainly due to infection in the patient’s respiratory tract, mostly seen in bacterial infections, and pharyngitis and bronchitis are considered the most likely. Clinically, symptomatic treatment with relevant and sensitive antibiotics, drinking more water, urinating more and moistening the airway are also beneficial to the condition, especially to reduce the formation of yellow clots. Patients can also eat fresh fruits and vegetables and drink more porridge and soup to make the condition recover as soon as possible. Appropriate application of phlegmolytic drugs, such as aminoglutethimide, bromhexine, acetylcysteine effervescent tablets and bronchodilators, such as aminophylline and dihydroxypropyl theophylline, under the guidance of doctors, can be a good treatment for cough and yellow lumps in sputum caused by chronic bronchitis and other diseases.