Children cough in the middle of the night and not cough during the day, can be physiological factors, cough variant asthma, common cold, gastroesophageal reflux, etc., according to the etiology of the choice of general treatment or compliance with the application of glucocorticoids, omeprazole and other drug therapy. 1. Physiological causes: such as dry air, low temperature and other stimulation of the respiratory tract; after strenuous exercise; inhalation of foreign objects, such as dust, dander, etc. can trigger the occurrence of cough, generally no treatment is needed, it is recommended to improve the living environment. 2. Common cold: usually accompanied by symptoms such as runny nose and fever. Most common colds are viral infections and can be cured on their own. Coughing is the body’s normal way of expelling germs, so it is not recommended to give your child cough suppressants, and you can relieve throat discomfort by taking honey or hot pear soup on a daily basis. 3. Cough variant asthma: occurs after contact with allergens, such as pollen, dust mites, cold air. It is characterized by paroxysmal irritating dry cough, which usually worsens at night. After going to the hospital to confirm the diagnosis, use nebulized inhaled glucocorticosteroids, such as budesonide, to improve airway inflammation under the guidance of the doctor. 4. Gastroesophageal reflux disease (GERD): The symptoms of GERD can be exacerbated at night when the child is lying down. Stomach acid and stomach contents irritate the throat, which can lead to coughing. You can elevate the child’s upper body at bedtime and do not eat before bedtime. If the symptoms are serious, you can follow the doctor’s instructions to give your child acid-suppressing drugs, such as omeprazole. In short, children who have a cough in the middle of the night and do not cough much during the day should go to the hospital in time and be treated under the guidance of a doctor. All of the above medications should be used under the guidance of a doctor, avoid self-medication.