HFMD is a viral infection, mainly enterovirus 71 infection, PCR test is used to detect the pathogen of the virus, and if the pathogen is detected, the diagnosis of HFMD can be confirmed. HFMD is a contagious disease that occurs most often in preschool children, especially in kindergarten children. Both the affected child and the latent infectious person are the source of infection, which can be transmitted through the gastrointestinal tract, respiratory tract and close contact. The main symptoms of patients are maculopapular rashes on the hands, mouth and anus, and some patients may develop fever. The majority of patients are mildly ill, while a few patients can present with severe symptoms such as meningitis and encephalitis.