High blood glucose, creatinine 34.6umol/L, if the blood glucose control is poor, the risk of progression to uremia cannot be excluded. High blood sugar and poor control, diabetic patients usually 5 to 10 years, about 30% will appear kidney damage, while a large amount of proteinuria, with the progression of the disease, proteinuria gradually increased, when increased to a certain extent, the permeability of the glomerular basement membrane of the kidney will be seriously impaired, with the creatinine increased, gradually progressing after the cause of uremia. Creatinine is a product of human muscle metabolism, and its normal value is between 53 to 106 μmol/L for men and 44 to 97 μmol/L for women. When kidney disease is in its early stages, creatinine is usually not elevated, and when creatinine is elevated in chronic kidney disease, irreversible damage to renal function is often already present. In diabetic nephropathy renal failure, usually creatinine around 450umol/L, it enters CKD stage 5 and requires renal replacement therapy. It is recommended that patients with high blood glucose should consult the hospital in time and actively control their blood glucose under the guidance of the doctor, and at the same time pay attention to the diet in their life, so as to avoid the progression of the disease, which may lead to the damage of other organs.