It is very important to care for patients with cerebrospinal fluid leaks that occur as a result of craniosynostosis because the greatest fear of cerebrospinal fluid leaks is that they can lead to intracranial infections. If an intracranial infection once occurs, its treatment period is relatively long. If it is a bacillary infection, and the mortality rate increases, so care is especially critical for cerebrospinal fluid leaks combined with cranial injury. Patients need to rest in a head-high position, the main purpose of which is to prevent intracranial infection due to cerebrospinal fluid reflux, and patients need to be instructed to avoid coughing, sneezing and blowing their nose. If the patient needs to lie on his or her side, he or she should try to lie on the affected side, for example, if the cerebrospinal fluid leak occurs on the left side, he or she should lie on the left side only.