Itchy bumps on the palms of the hands may be caused with eczema, tinea cruris, palmoplantar pustulosis and other diseases. 1. Eczema: Eczema on the hands is an eczematous disease of the hands, which is considered to be related to family genetics, contact with allergens, diet and other factors. It leads to dry, red, edema-like, hypertrophic blisters, plaques, and scaly lesions on the palms, backs of the hands, and finger areas, which may be accompanied by itching. 2. Ringworm: ringworm is caused by fungal infections, such as Trichophyton rubrum, Trichophyton mustelii, and Plaster-like microsporidia. If tinea cruris is blistering and scaly, it may lead to deep blister-like lesions and itching between the fingers and on the palm. 3. Palmoplantar pustulosis: the specific cause of palmoplantar pustulosis is not yet completely clear, may be related to genetic, immune and other factors, resulting in local erythema, pustules, flaking and other manifestations. If you have small bumps on the palm of your hand, it is recommended that you go to the dermatology department of a hospital to look for the cause of the bumps, and then combine it with your doctor’s advice to treat the cause of the bumps.