Drinking alcohol the next day has been vomiting bitter water may be related to bile reflux, peptic tract acute ulcer, etc., can take metoclopramide, omeprazole, etc. for treatment. 1. Bile reflux: Excessive drinking causes gastric mucous membrane irritation, causing recurrence of cholecystitis, which in turn causes bile reflux and vomiting of bile. Metoclopramide and other drugs to protect the gastrointestinal tract can be taken for relief. 2. Acute ulcers of the digestive tract: (1) Acute gastritis: alcohol stimulates the mucous membrane of the digestive tract, causing congestion, edema and erosion of the mucous membrane, causing the gastrointestinal tract to reverse peristalsis, which leads to the symptoms of acute enteritis, such as nausea and vomiting, and bile is often accompanied by bile in the vomit. Omeprazole, rabeprazole and other acid-suppressing drugs can be taken for treatment. (2) Cholecystitis: Alcohol leads to recurrence of cholecystitis, causing bile reflux and symptoms such as vomiting and spitting out bile. The onset of cholecystitis is relatively acute, self-medication is not recommended, and should be treated promptly by a doctor. The above drugs are prohibited for those who are allergic to them, and they should all be taken in accordance with medical advice. There are many other reasons that lead to the second day of drinking alcohol has been vomiting, we recommend that patients go to the regular hospital in a timely manner, clear the cause of the disease, under the guidance of the doctor for targeted treatment or treatment.