Negative hepatitis B surface antigen is normal. Hepatitis B surface antigen (HBsAg) is the outer shell of the hepatitis B virus (HBV), present in the blood, body fluids and secretions of infected individuals, usually present at the same time as HBV, and is one of the most important oh serologic markers for determining HBV infection. Hepatitis B surface antigen negative is normal. If the hepatitis B surface antigen is positive, it indicates that the body is infected with hepatitis B virus, which is commonly found in the latent state after HBV infection, the acute stage of viral hepatitis B, chronic hepatitis B and other patients, but also in hepatitis B virus carriers. Hepatitis B surface antigen positive, the body is not only infected with hepatitis B, but also contagious, attention should be paid to blocking the transmission to avoid spreading to others, at the same time need to actively seek medical treatment. Hepatitis B surface antigen negative is normal, can be further checked whether the hepatitis B surface antibody is positive, if negative, it is recommended to carry out hepatitis B vaccination, it is recommended that patients consult a professional physician.