Major triple positive Hepatitis B surface antibody 0.00 usually means 0.00 IU/ml, indicating that one has been infected with Hepatitis B and the virus is at a high level of replication. Major triple positive refers to being positive for Hepatitis B surface antigen, Hepatitis B e antigen, and Hepatitis B core antibody, while being negative for Hepatitis B surface antibody and Hepatitis B e antibody. If the test is quantitative, the Hepatitis B Surface Antibody is 0.00 IU/ml. This condition indicates that the tested person is infected with Hepatitis B. Usually, the Hepatitis B virus is more replicating and contagious, and the body has no immunity. When it is found that the person is infected with Hepatitis B Triple III, further tests such as liver function, Hepatitis B virus test, alpha-fetoprotein, liver ultrasound, liver hardness and so on should be improved. If liver function is impaired, liver fibrosis or cirrhosis exists, and the virus test is positive, it is necessary to take antiviral medication, such as entecavir, tenofovir, etc., under the guidance of a professional physician’s interview.