Which is more serious, the roughness of the gastric mucosa or the granularity, can not be determined, according to the specific cause of the disease. Roughness of gastric mucosa is more common in inflammation of stomach, which is a kind of performance description under electronic gastroscopy. Under normal circumstances, gastric mucosa should be smooth, if there is roughness, it is more common in inflammatory diseases, such as superficial gastritis. In addition, when early gastric cancer is examined by gastroscopy, the gastric mucosa will be rough, easy to bleed when touched, and usually there will be patchy congestion and erosion. Granular gastric mucosa is also an abnormal manifestation, which may be caused by improper diet, gastritis, gastric ulcer, gastric polyp and other diseases. Early gastric cancer may also show granular changes, which should be taken seriously. Both roughness and granularity of gastric mucosa may be more serious, which should be taken seriously and further examination should be carried out to clarify the diagnosis.