Fever in renal insufficiency, first of all, should clarify the cause of the disease, if it is caused by bacterial infection, can take antibiotic treatment that has less impact on renal function. If the fever is too high, according to the renal function, you can take acetaminophen tablets, ibuprofen extended-release capsules and other non-steroidal anti-inflammatory drugs as prescribed by the doctor. Many drugs are metabolized by the liver and excreted by the kidneys. When taking antibiotics, NSAIDs and other drugs in patients with renal insufficiency and fever, the dose of the drug should be adjusted. Acetaminophen tablets and ibuprofen extended-release capsules are prohibited for patients with severe hepatic and renal insufficiency. Patients with renal insufficiency fever should go to the hospital in time, under the guidance of a professional physician to clarify the cause of the disease, and use drugs that have less impact on the kidneys to treat the disease, do not self-medication.