Lower lip twitching is caused by: first, the consideration is caused by factors in the external environment physiological muscle spasm, the most common factors are cold or overheating caused by pain stimulation, itself does not occur pathological changes, but in the stimulation will be slowly relieved, it is not necessary to do any special treatment. Organic lesions in the process of facial nerve travel any kind of stimulation can cause this situation, clinically it is a functional lesion, such as insomnia patients are prone to; second, consider the peripheral neuritis caused by involuntary twitching of the lips. Once found to have twitching, it is recommended that the best to the regular hospital for a comprehensive examination, and make a diagnosis and differential diagnosis, and then according to the specific causes to make targeted scientific and reasonable program.