Waking up with stomach pain in the middle of the night may be caused by duodenal ulcer, gastrointestinal spasm and bad eating habits. Having pain when you are hungry and the pain disappears immediately after eating is a problem with gastric power, which is a typical symptom of duodenal ulcer, i.e., you will have hunger pain, midnight pain, and fasting pain. In the middle of the night, if the stomach has paroxysmal pain, it may be a spasm of the gastrointestinal tract, so it will be awakened by pain. If you eat spicy, stimulating, raw and cold food and drinks such as spicy hot, barbecue, fried and cold beer at night, it will stimulate the gastric mucosa leading to stomach distension and pain, and you will even be awakened by pain in the middle of the night. Bad eating habits also include overeating, eating too much at night, the stomach can not effectively absorb too much food, increasing the burden on the stomach, and the same abdominal pain in the middle of the night.