Sleep disorders encompass many forms, such as difficulty falling asleep, early awakening, difficulty maintaining sleep, decreased sleep quality, and disturbed sleep structure. There are many drugs used to treat sleep disorders. Commonly used drugs include: benzodiazepine sedative-hypnotics, new non-benzodiazepine hypnotics, melatonin receptor agonists and antidepressants with hypnotic effects. Commonly used benzodiazepines include: 1, short-acting class, such as triazolam, midazolam, mainly for the treatment of patients who have difficulty falling asleep; 2, medium-acting class, such as lorazepam, eszopiclone, alprazolam, mainly for the treatment of patients with shallow sleep and easy waking; 3, long-acting class, mainly diazepam, clonazepam, mainly for patients who wake up early. New non-benzodiazepine hypnotic drugs include zolpidem and dexrazopiclone. These drugs have a rapid onset of action, short half-life, generally do not produce daytime sleepiness as well as long-term use without significant adverse drug reactions. Melatonin receptor agonists include ramelteon and agomelatine, which can shorten sleep latency, improve sleep efficiency, adjust sleep structure and increase total sleep time. Other antidepressants with sedative effects include mirtazapine in small doses as well as trazodone.