The pessary can be kept in the refrigerator, but not in the frozen layer, but in the fresh layer, because the pessary at room temperature may melt at higher temperatures and cause corresponding effects in the process of use. This phenomenon does not occur if it is kept in the fresh layer. It is better to take it out of the fresh layer and put it at room temperature before use and use it when the temperature rises to avoid local irritation of the vagina due to the low temperature, so this should be noted. If allergies occur during the application of the pessary, stop using the medication and do not have sexual intercourse during the application of the pessary in order not to reduce the effectiveness of the medication. After the clinical symptoms have completely disappeared, you can go to the hospital for a review.