What are the complications of titanium mesh repair of cranial defects? The brain, as an important part of the human body, plays an important role in driving mood changes, decision-making and action in daily life. While people cannot help but praise it for its powerful functions, they are unaware that there is a natural helmet on the surface of the brain that is always protecting our brain from external injuries, which is our skull. In spite of a thousand precautions, still can not avoid the advent of some accidents, such as car accidents, collision, falling down the stairs, etc. will make our brain injury, many patients need to perform de-bone flap decompression surgery for treatment, leaving behind skull defects, serious head collapse. Without the protection of the skull, it is not only easy to cause instability of intracranial pressure or intracranial abnormality, but also easier for patients to develop psychological disorders, low self-esteem, depression, irritability and so on. Therefore, timely cranial bone repair is needed. Although the neurosurgery department of some hospitals in China has widely used titanium mesh cranial repair for patients, but the postoperative feedback is poor. So, what are the contraindications after titanium mesh skull repair? It is found that titanium mesh is essentially a metal property, take the cover type repair method, and the material performance is not good, tissue compatibility is not ideal, thermal insulation is not good, hardness is not high, shaping effect is not very good, there may also be many postoperative complications, common rejection of infection, titanium mesh exposure, CT MRI is affected, and so on. Therefore, patients should seek for more advanced and mature technology when preparing for cranial repair. At present, Zhu Anlin’s team in our hospital carries out polyetheretherketone peek cranial repair and plastic surgery, with the advanced concept of precise repair + cosmetic plastic surgery, based on the summary of many cases, and realizes four technical innovations. This technology, with peek as the implant material, can effectively avoid the many deficiencies that exist in titanium mesh cranial bone repair. In addition, this technology develops a personalized repair and plastic surgery plan for each patient with cranial defects, which ensures that the two sides are opposite each other after the surgery and the shape is beautiful and aesthetically pleasing. There are also unique material edge, thickness, mesh aperture design, unique tissue separation and reset technology, cosmetic plastic surgery technology, and ultimately achieve anatomical integrity, functional perfection, aesthetic unity.