The swelling and pain in the corners of the eyes of patients may be caused by visual fatigue, glaucoma, infection, trauma and so on. 1. Visual fatigue: if the patient has prolonged contact with computers, cell phones and other electronic products, it may lead to visual fatigue, and the patient may experience discomfort such as soreness and dryness in the eyes, as well as swelling and pain in the corners of the eyes. 2. Glaucoma: acute attack of glaucoma, the patient’s intraocular pressure rises, may also appear in the corner of the eye swelling and pain and other symptoms. 3. Eye infections: Conjunctivitis, keratitis, blepharitis and other infectious diseases of the eye patients, in the inflammation stimulation, patients may also appear eye swelling and pain, may also be accompanied by photophobia, tearing and other discomfort symptoms. 4. Trauma: Eye injuries such as impact and pressure injuries can also cause swelling and pain in the corners of the eyes. It is recommended that patients with significant swelling and pain in the corners of the eyes should consult a doctor in a timely manner to assess their condition and follow the doctor’s instructions for treatment.