Breastfeeding by mothers who are positive for hepatitis B surface antigen does not increase the risk of infection in the infant. Therefore, as long as the newborn has received hepatitis B immune globulin and hepatitis B vaccine within 12 hours of birth, breastfeeding is permitted, but breastfeeding should be temporarily discontinued if there is damage to the nipple and if the child develops mouth ulcers. Regarding breastfeeding, many doctors believe that breastfeeding can cause mother-to-child transmission, but there are many studies that clarify this concern. Breastfeeding is important for the healthy development of the pediatric population and should not be taken away from the pediatric population lightly. In fact, there is no longer a need for concern when a pediatric patient is immunized at birth with hepatitis B vaccine combined with hepatitis B immune globulin. Excerpts from “Hepatitis B Basic and Clinical” by Locke Resistance First. Newborns should be vaccinated against hepatitis B within 24 hours, as early as possible, according to the “0, 1, 6 program”. By doing so, more than 95% of newborns can be protected from mother-to-child transmission of hepatitis B by their mothers of the previous generation, and obtain a healthy body. The effectiveness of PMTCT can be significantly improved by administering Hepatitis B immunoglobulin as early as possible within 12 hours after birth, and at the same time administering 10 μg of recombinant yeast or 20 μg of Chinese hamster oocyte (CHO) Hepatitis B vaccine. Alternatively, one injection of hepatitis B immunoglobulin can be given within 12 hours of birth, followed by a second injection of hepatitis B immunoglobulin 1 month later, along with a single injection of 10 μg of recombinant yeast or 20 μg of CHO hepatitis B vaccine, and second and third injections of hepatitis B vaccine (10 μg each of recombinant yeast or 20 μg of CHO hepatitis B vaccine) given at intervals of 1 and 6 months, respectively. Although the latter is not as convenient as the former, its protection rate is higher than that of the former. After completing either of the above two, the child can be breastfed by the HBsAg-positive mother after birth, but care should be taken to keep the nipples clean and not ruptured and bleeding.