The indications for pancreaticoduodenectomy are most likely to include benign disease as well as malignant disease. Most people have malignant diseases and relatively few have benign diseases. Malignant indications include: 1. pancreatic cancer, the site of pancreatic cancer is cancer of the head of the pancreas including cancer of the hook; 2. cancer around the jug abdomen, cancer around the jug abdomen is a variety of tumors including cancer of the lower end of the bile duct, duodenum, duodenal papilla, cancer of the head of the pancreas pancreatic. Therefore, peri-pot belly tumor is also one of the main indications for pancreaticoduodenectomy; 3. Other tumors including mucinous cystadenoma, which may develop into pancreatic cancer in patients, also need to undergo pancreaticoduodenectomy.