It has been found that with the increase of social pressure and the change of people’s lifestyle and diet, the number of migraine patients is increasing, and some patients with neuropathic headache have similar symptoms to migraine, which brings many problems to patients on their way to seek medical treatment. So, how to distinguish migraine from neuropathic headache? The difference between migraine and neuropathic headache: Migraine is usually characterized by throbbing pain on one side, more common in the forehead, temporal area, and around the orbits, with an attack time of 4-72 hours, accompanied by nausea, vomiting, and photophobia. Genetic factors, lack of sleep, poor living habits and diet may trigger migraine. And neuropathic headache is mostly caused by mental tension and anger, and some female patients have neuropathic headache due to endocrine change, personality change of menopause which causes patients to be impatient and irritable, tense mind and mental stress, and the symptoms are persistent dull pain, pressure and heaviness in the head, which easily lead to physical and mental emaciation, physical strength loss and hidden pain in the brain. The harm of headache to people: Whether migraine or neuropathic headache, if not treated in time, it will bring serious adverse consequences to patients’ daily life and work. 1.Seriously affects the life, the most direct one is to affect the sleep. Because of the lack of sleep, there is no energy during the day, and work is greatly affected. Moreover, some patients have headache when they work, which is very delayed. 2.The pain is unbearable. Normal people also have headache when they are tired, nervous, or have cold, but this situation is only short-lived, and it usually returns to normal in a few days. If it does not recover as early as possible, but also frequent attacks and unbearable pain, it is necessary to seek timely medical attention. 3.Bringing serious psychological burden, when a person suffers from headache for a long time, his personality will slowly change and become irritable. And because of the long treatment, life is greatly affected, psychological fragility and loss of confidence. Generally light migraine can be treated with medication, and the medication treatment plan varies for different stages of migraine. Patients are advised to choose the right medication for themselves with the advice of their doctors. For migraine patients with poor results of medication, surgical treatment can be tried. Microvascular decompression for migraine is more effective.