Drugs such as roxithromycin are mainly metabolized in the liver, repeatedly circulated in the liver and absorbed by the intestines to exert their medicinal effects, and the metabolism of alcohol is also mainly in the liver, so drinking alcohol after taking the drug tends to aggravate the damage to the liver. At the same time, the drug circulation is accelerated, which tends to increase the toxic effect of the drug. Most drugs need 2-3 days to be metabolized completely, so it is appropriate to drink alcohol after taking roxithromycin for 2-3 days. The adverse effects of roxithromycin are easy to stimulate the gastrointestinal tract, abdominal pain and discomfort, nausea, vomiting and other symptoms, you can choose to take it after meals to reduce the side effects of the drug. After taking the medicine, pay attention to drink more water, which can accelerate the metabolism of the drug, and it is best to drink alcohol a week after taking the medicine.