The first may be excessive masturbation, frequent sex and other physiological factors caused by edema at the coronal groove of the penis, without treatment. Secondly, it may also be caused by glans inflammation, foreskin inlay, etc., need to take medication, manipulation reset, surgical treatment for the cause of the disease. 1. Physiological factors: if men masturbate too much or frequent sex may stimulate penile coronal angioneurotic edema, which is a normal physiological phenomenon, can not be treated. Generally, the symptoms will improve on their own. 2. glans: edema of the penile coronal groove may be caused by glans, for aerobic bacterial infection caused by glans need to follow the doctor’s instructions oral erythromycin, amoxicillin and other antibiotics. For Candida albicans infection caused by glans, you need to follow the doctor’s prescription oral itraconazole, fluconazole and other antifungal drugs. 3. circumcision inlay: circumcision inlay can also lead to edema in the coronal groove of the penis, patients with circumcision inlay, the doctor will apply lubricant on the hand and then hold the circumcision edema and glans area, and then gradually increase the pressure, so that the foreskin and glans reset. For patients whose maneuvers are ineffective, dorsal circumcision is needed. There may be other reasons for the edema at the coronal groove of the penis, it is recommended to actively seek medical attention, under the guidance of a professional physician for diagnosis and treatment. The above drugs need to be used under the guidance of a professional physician, to avoid blind use of drugs, so as not to aggravate the condition.