Hyaluronic acid is injected into the skin to fill in the wrinkles and fill up the skin, thus reducing the effect of wrinkles. This method has the advantages of being painless, minimally invasive, short treatment time, no recovery period to go to work, etc. It has a good effect of wrinkle reduction and immediate results. As hyaluronic acid is a substance in the basal layer of human skin, when hyaluronic acid filler is injected into the skin, it will be gradually absorbed and decomposed by the body continuously over time. However, each person’s physique is different, some people absorb it more quickly, some people absorb it more slowly, so the time to maintain the effect of hyaluronic acid wrinkle removal will vary. The effect of one injection usually lasts 6-12 months and is gradually absorbed by metabolism. If additional injections are given, the effect can be maintained for about 18-24 months. In addition, it should be noted that not all wrinkles are suitable for hyaluronic acid injection, which is mainly used for static wrinkle removal, such as forehead lines, decreases in wrinkles. For dynamic wrinkles, wrinkles caused by sagging skin, etc., other more suitable counterparts should be considered.