It is safe to say that calcium tablets cannot be taken for a long time. Long-term calcium intake is likely to lead to calcium salt deposition, which, in addition to constipation, may also cause precipitation in the kidneys and lead to the formation of kidney stones. There is even the view that long-term supplementation of calcium tablets may induce some cardiovascular and cerebrovascular diseases, so calcium supplementation should be carried out under the guidance of a doctor. Especially for some patients with severe osteoporosis, such as those given zoledronic acid treatment, the amount of calcium supplementation should be increased at the same time of treatment to promote calcium deposition on the bone. In fact, the daily diet is rich in calcium, and we can effectively prevent osteoporosis by eating more milk, fish, shrimp and other foods with high calcium content, more sunshine and proper functional exercise. The few patients diagnosed with osteoporosis can meet their body’s needs with proper supplementation of calcium tablets and vitamin D. However, such medication is cyclical and cannot be taken for life to avoid causing other more adverse reactions.