Cranial defects are common sequelae after craniotomy due to craniocerebral injuries, cranial osteoma and other craniotomies. When the defect site exceeds 3 cm, it not only seriously affects the patient’s aesthetic appearance, but also will appear a variety of clinical symptoms such as headache, dizziness, mood changes, defect area throbbing, etc., and even can induce epilepsy, which seriously affects the patient’s normal work and life. Therefore, once the skull is defective, cranial repair should be done as soon as possible to protect the brain tissue, relieve clinical symptoms and restore the patient’s aesthetic appearance. PEEK material is a very mature material, in many countries has been widely used as a cranial bone repair material, but not many domestic, the reason is that PEEK material is a new type of repair material, due to the patient to do cranial bone repair is not a very good understanding of the PEEK material, restricting the wide application of PEEK material. PEEK material for cranial bone repair is not only better than other high temperature resistant plastics, and has high strength, high fracture toughness and good dimensional invariance, is currently a good material for cranial bone repair. peek cranial bone repair material is currently more advanced surgical materials, peek cranial bone repair price according to the degree of illness of different repair. It is recommended that patients go to a regular hospital for surgery as soon as possible, not to delay the disease, early treatment can be early recovery.