Interferon can be used during the antiviral period of hepatitis B teratitis B. There are contraindications to interferon, and adverse reactions may occur, not all patients with hepatitis B teratitis B are suitable for interferon, and should be guided by a doctor to use the medication. Interferon is a broad-spectrum antiviral agent, which can inhibit the replication of hepatitis B virus and play the role of immunomodulation, interferon during the antiviral period of hepatitis B triple III can play a better antiviral effect. Playing interferon may have fever, headache, body fatigue, muscle pain and other adverse reactions; pregnant women, lactating women, people who are allergic to interferon and its components, patients with autoimmune hepatitis or a history of autoimmune diseases, patients with decompensated liver function, patients with a history of severe or unstable heart disease, hemoglobinopathies and so on, are forbidden to use this drug. Hepatitis B small triple yang antiviral period whether to play interferon should go to the regular hospital after consultation, by the professional doctor to decide, the patient can not arbitrarily use the drug.