Insomnia in middle-aged and elderly people is mostly caused by menopause, as a result of endocrine dysfunction. Discomfort such as sleep disorders, palpitations and sweating can be regulated by taking oral glutamate and tranquilizer. Patients are advised to take physical exercise, do some outdoor sports, develop good habits, sleep and wake up on time, do not stay up late, do some aerobic exercises before going to bed, as well as drink a glass of hot milk, soak your feet in hot water, also listen to gentle music before going to bed, and avoid drinking strong tea and coffee before going to bed to avoid overexcitement, which will help improve patients’ sleep. It may also be caused by anxiety or depression. Patients with anxiety disorders, who also experience anxiety, irritability, panic and fear, are mainly treated with oral buspirone, or tandospirone, and can also take oral Laura. In the case of depression, the main treatment is the application of citalopram, but also Dextran, etc.