The main role of glomerular filtration is detoxification and drainage. The kidney has a very important role in the human body, and its main role is to detoxify and drain water, and the glomerulus is mainly responsible for this function. The glomerulus is very much like a filter, where the blood circulates and dissolves the toxins metabolized in the blood in the urine to be excreted from the body, thus achieving the purpose of detoxification and drainage. If toxin excretion is impaired and toxins accumulate in the body, it will cause a series of serious symptoms such as nausea, vomiting, loss of appetite and uremic encephalopathy. If water excretion is impaired and water is stored in the body, it will cause edema, elevated blood pressure, heart failure, cerebral edema and a series of other symptoms. From here, we can find that glomerular filtration is very important for the body. In order to prevent the reduction of glomerular filtration, it is important to avoid nephrotoxic drugs such as ibuprofen or gentamicin, for example. If you already have underlying kidney disease, you should actively give treatment to prevent further reduction of glomerular filtration.