Pioglitazone is mainly used for the treatment of diabetic patients, and common side effects include edema and induction or exacerbation of heart failure. Pioglitazone is a thiazolidinediones hypoglycemic drug mainly indicated for the treatment of patients with type 2 diabetes mellitus whose blood sugar cannot be controlled by diet and exercise alone. It is contraindicated in patients who are allergic to this product and thiazolidinediones, heart failure. This drug should be used with caution in patients with hepatic or renal dysfunction, heart disease, etc. Common side effects of this drug include edema, dyspnea, hypoglycemia, and induced or aggravated heart failure. Patients who need to be treated with pioglitazone should use the drug under the supervision of a doctor, and it is recommended to go to the hospital if side effects occur after using the drug.