Washing face with toothpaste cannot remove spots. Toothpaste is a common cleaning product in daily life, its composition is mainly friction agent, containing calcium carbonate, calcium hydrogen phosphate, silicon dioxide, aromatic agent, thickening agent, etc., which has a cleaning effect on teeth. Washing face with toothpaste may remove dirt on face, but it cannot achieve the effect of removing spots. Moreover, it should be noted that if you wash your face with toothpaste frequently, the irritating ingredients contained in it may also destroy the protective effect of skin stratum corneum, stimulate the formation of sensitive skin, and may even lead to skin infection, so don’t wash your face with toothpaste to get rid of spots without permission. If you want to get rid of spots, you can choose the following methods: 1. Apply some light spot cream or use hydrating mask, which can play the role of lightening. You can also use vitamin E cream or skin care products containing hydroquinone, and you can also choose fractional CO2 laser treatment or photorejuvenation. 2. Try to avoid ultraviolet radiation on the skin in daily life, apply sunscreen and play umbrella when you go out, which can effectively avoid the formation of spots. It is recommended that patients who already have spots should maintain an optimistic attitude, not to be too hasty, and should keep regular work and rest and avoid staying up late. Eating more vegetables and fruits such as tomatoes and lemons to replenish vitamins and proteins for themselves and avoiding stimulating spicy or greasy food can also improve the skin condition.