Is gamma-glutaminase 80 a problem?

In general, the normal reference range of γ-glutaminase is 10-60U/L for men and 7-45U/L for women (the reference range can be different under different testing methods, the specific local hospitals shall prevail), and γ-glutaminase 80 suggests that it is high, which is an abnormal phenomenon. γ-Glutaminase is the enzyme that transfers the γ-glutamyl group from glutathione to another peptide or amino acid. γ-Glutaminase is most highly expressed in the kidneys, followed by the pancreas and liver. Normal human gamma-glutamyltransferase is derived primarily from the liver, and serum gamma-glutamyltransferase is elevated when hepatic synthesis is hyperactive or biliary excretion is impaired. Elevated γ-glutamyltransferase can be seen in acute viral hepatitis, alcoholic hepatitis and other liver diseases, but also can be seen in primary biliary cirrhosis and other biliary tract obstructive diseases, as well as pancreatitis, prostate tumor and so on. It is recommended that the patient should consult a doctor in time to make a clear diagnosis and carry out targeted treatment under the guidance of the doctor.