Diabetic ketoacidosis, with hyperglycemia, ketosis and acidosis as the main manifestations, is a serious metabolic disorder syndrome caused by the combined effect of insufficient insulin and excessive antagonistic insulin hormone. Its causes include primary etiology, causative factors and so on. 1. Primary etiology: serious disorders of sugar, fat and protein metabolism caused by severe insulin deficiency or abnormal elevation of glucagon (e.g., glucagon), such as type 1 diabetes mellitus with a tendency to spontaneous DKA. 2. Triggers: Type 2 diabetes is prone to diabetic ketoacidosis under a number of triggers, such as interruption of insulin therapy or inappropriate reduction, various stress, alcoholism, and the application of certain drugs such as glucocorticoids. Diabetic ketoacidosis can appear fatigue, nausea and vomiting, drowsiness, and the smell of rotten apples in the breath, etc. If you feel unwell, you should seek medical attention.