35-year-old man with age spots belongs to seborrheic keratosis, the current etiology and pathogenesis is unknown, may be associated with delayed maturation of keratinocytes and abnormal expression of cell cycle regulatory factors, etc., in which the skin aging, heredity, sun exposure, air pollution, infections and other factors can induce the formation of age spots. 1. Skin aging:The incidence of adults over 40 years old is increasing, and seborrheic keratosis is associated with aging skin. 2. Heredity:Seborrheic keratosis multiforme has a certain genetic susceptibility, which is autosomal dominant inheritance with different epigenetic rates. 3. Sun exposure: Long-term sun exposure can damage the skin and accelerate skin aging. 4. Air pollution: exposure to airborne pollutants is significantly associated with exogenous skin aging. 5. Infection:Human papillomavirus infection in the genital area may be a predisposing factor for seborrheic keratosis. If the face with age spots, you can go to the regular hospital dermatology consultation, under the guidance of the doctor reasonable treatment, usually do a good job of skin sunscreen.