Stool blockage will cause toxins to be absorbed into the bloodstream through the intestines, easily damage the liver, brain, and induce intestinal ulcers or intestinal cancer, resulting in constipation, and forceful defecation can easily induce cardiovascular and cerebrovascular diseases. 1. Stool blockage will cause hydrogen sulfide, histamine and other toxic substances to be absorbed into the bloodstream, increasing the burden of liver detoxification, resulting in liver cell damage. 2. Stool blockage will cause hydrogen sulfide, indole and other toxic substances to be reabsorbed into the bloodstream and enter the brain, damaging the central nervous system and leading to an increase in the incidence of dementia in the long term. 3. A large amount of persistent feces can compress the intestinal mucosa, causing intestinal ischemia and necrosis, forming intestinal ulcers, and patients often have lower abdominal pain, blood in the stool and other symptoms. 4. Toxins and other carcinogens are stored in the intestines for a long period of time when the stool is clogged, coupled with long-term inflammation to stimulate the intestinal wall, the risk of intestinal cancer increases. 5. Middle-aged and old people have chronic diseases such as hypertension or coronary heart disease, which can lead to constipation and high intra-abdominal pressure and increased burden on the heart, which can suddenly induce angina pectoris, myocardial infarction, cerebral infarction and other cardiovascular and cerebral vascular diseases. Long-term obstruction of the bowels is especially harmful to middle-aged and elderly people. It is recommended to consult a doctor as soon as possible, complete the examination, and give appropriate treatment to alleviate the symptoms after a clear diagnosis.