The first thing you need to do is to make a clear diagnosis of sore throat, such as acute laryngitis, acute epiglottitis, laryngeal cancer, etc. The treatment needs to be based on the cause of the disease and the symptoms of the targeted choice in order to achieve the best results. 1. Common cold: often caused by viral or bacterial infections, such as the occurrence of severe sore throat symptoms, under the guidance of the doctor can apply antipyretic and analgesic drugs, such as ibuprofen. Antibiotics, such as moxifloxacin, penicillin and cefepime, should also be used to treat the cause of infection. 2. Acute epiglottitis: it mostly develops when there are infections, allergies and physical and chemical factors stimulation, with epiglottis edema and congestion followed by sore throat. Glucocorticosteroids should be used as the main active treatment, such as dexamethasone, prednisone, etc. to eliminate edema and obstruction, and at the same time, the anti-infective treatment should be given with sufficient quantity and duration, such as ceftriaxone and azithromycin. 3. Laryngeal cancer: radiotherapy, chemotherapy, surgery, including partial laryngectomy, total laryngectomy, etc. are needed to improve the symptoms and increase the survival period, while oral drug treatment is mostly for relieving pain and discomfort and local anti-inflammation, such as compound borax gargle, compound furacilin gargle, gargle with iodine laryngeal tablets and watermelon cream tablets. It is recommended that when the organism has a swollen and sore throat, it should consult a doctor in time to find out the cause, and standardize the use of medication and treatment under the guidance of the doctor.