52 years old menstruation for 4 months did not come, and now come black color may be considered to be caused by perimenopausal syndrome. Perimenopausal syndrome is mainly caused by the decline of female ovarian function, resulting in neuroendocrine changes in the body, and is considered to be related to genetic, disease, environmental, medical and other factors. Patients often experience menstrual disorders, which can be characterized by irregular menstrual cycles, long duration of menstruation, and increased or decreased menstrual flow. Generally 6 consecutive months without menstruation is considered to be complete menopause, 4 months without menstruation and then come back, it should be the cause of irregular menstruation and low menstrual flow. It is recommended that 52-year-old patients who have not had menstruation for 4 months and now come with darkening, consult the hospital for ultrasonography to determine whether there are other diseases.