Uric acid is one of the most sensitive indicators of the state of kidney function in the human body.

Blood uric acid is the body’s old cells, and food, especially purine-rich foods (such as animal offal, seafood, etc.) in the body during metabolism, the oxidative decomposition of its nucleic acid products there are purines (this endogenous purines accounted for 80% of total purines). Under normal circumstances, the body’s uric acid about 1200 milligrams per day, about 600 milligrams of new generation, while 600 milligrams of excretion, in a balanced state. But if the body produces too much to excrete or uric acid excretion mechanism degradation, the body retains too much uric acid, when the blood uric acid concentration is greater than 7 mg / dl, so that the human body fluids become acidic, affecting the normal function of the body’s cells, long-term disregard will trigger gout. More and more studies have found that uric acid is a response to the state of renal function is very sensitive indicators, its elevation from a certain degree reflects the renal mesenchyme and renal tubular function to appear certain obstacles (uric acid reabsorption and excretion), it is not like creatinine, urea nitrogen, and other indicators simply respond to the kidney’s nitrogen metabolism excretion of the function of the products, uric acid itself is a strong pro-inflammatory response to the substance, persistent hyperuricemia will cause it in all parts of the human body, and the body’s body will be affected. Uric acid itself is a strong pro-inflammatory substance, persistent hyperuricemia will cause it to be deposited in various organs of the body. The part of the body where it is deposited will definitely cause inflammation of the local tissues. Gout is only an inflammatory reaction caused by uric acid deposited in the joints, which can be seen and felt, so it is easy to draw attention to. However, the inflammatory reaction of uric acid deposition in the heart and kidneys is not visible to everyone, and even non-specialist doctors do not necessarily recognize this lesion and its serious consequences. Hyperuricemia is harmful to the human body is highlighted in the following aspects: 1, persistent hyperuricemia in certain states (fatigue, colds, large sports activities), can trigger an acute gouty attack, and then transformed into chronic gout, and then the formation of gout stones. 2, because most of the uric acid in the discharge out of the body have to go through the kidneys, if the concentration is too high, in the acidic state of the human body is very easy to form crystals and deposition in renal tissues, the light is the formation of stones, the heavy is caused by chronic tonic nephritis, uric acid nephropathy, etc., the early stage of these renal damages may not be able to see any manifestation of, once the clinical symptoms appear, often difficult to reverse. 3.Causing elevated blood sugar and blood fat. Clinically, high blood lipids, high blood sugar is basically synchronized with the existence of high uric acid, high uric acid patients with a large proportion of the population, can cause this problem is mainly due to urate damage to the arterial endothelial cells, and through the purine metabolism, as well as other metabolic ways to promote the disease. 4, cause atherosclerosis. Atherosclerosis is a more serious manifestation, when the arteries appear hardening, basically there will be high uric acid reaction.