Physiologically, the sense of taste is perceived by the taste buds on the papillae of the tongue, and the loss of taste is mainly due to the following diseases: First, central nervous system diseases, such as cerebral infarction and cerebral hemorrhage, which can damage the taste center and cause loss of taste. Second, anxiety, depression, prolonged severe anxiety, depression patients will also appear taste loss or disappearance. Third, mechanical damage to the tongue papillae, some patients like to scrape the tongue, prolonged scraping of the tongue can lead to damage to the tongue papillae and thus abnormal taste sensation. Fourth, infectious diseases, most commonly viral infections, such as upper respiratory tract infections, gastrointestinal viral infections, etc. Fifth, a long time to eat spicy food, excessive spicy stimulation can lead to damage to the taste buds, resulting in the loss of taste sensation, disappear. The loss of taste should be promptly seen by a hospital to identify the cause and treat the cause.