One third of pancreas cut, bile resection, duodenectomy, one third of gastrectomy may be patients with pancreatic head cancer complicating distant metastasis, radical surgical resection and symptomatic treatment. Pancreatic head cancer belongs to pancreatic cancer with high malignancy degree, and it is very easy to metastasize. Common metastatic pathways of pancreatic cancer include lymphatic metastasis, nerve metastasis, direct infiltration, hematogenous metastasis and so on, and common metastatic sites of pancreatic head cancer include stomach, gallbladder and other parts, which are in line with the above resection sites. Considering the infiltration metastasis of pancreas, at present, patients with pancreatic cancer that has already metastasized in clinical practice can be treated by radical surgery if they meet the indication of surgery, and then radiotherapy can be used after surgery for adjuvant treatment. For patients with pancreatic cancer, they need to standardize the treatment under the guidance of doctors to prolong the survival period and improve the symptoms as much as possible.