The left hand is cool and the right hand is hot, which may be related to physiological phenomenon, cerebrovascular disease, nerve compression and other factors. 1. Physiological phenomenon: when people because of improper posture leads to the left hand long-term extrusion, local blood circulation is not smooth, it will lead to the left hand skin temperature is relatively low, touch will feel the left hand cool right hand hot. 2. Cerebrovascular disease: for example, when the patient has a transient cerebral ischemic disease, the left side of the body once the ischemic circulatory disorders, may lead to the left hand can not get enough blood supply, the local skin temperature is lowered, thus appearing in the phenomenon of the left hand cool right hand hot. 3. Nerve compression: When the nerve controlling the left hand is compressed or damaged, the left hand may be cool and the right hand may be hot, such as those who have nerve root cervical spondylosis, this phenomenon may occur. If the left hand is cold and the right hand is hot, it is recommended that the patient should go to the hospital in a timely manner to clarify the cause of the disease and receive diagnosis and treatment.