Cranial repair is a relatively routine procedure in neurosurgery and the technique is very well established. At present, in cranial bone repair, the selection of appropriate repair materials is very important. A good repair material can achieve a more ideal repair effect and reduce the incidence of postoperative discomfort; if the repair material is not properly selected, various problems may arise. A more widely used cranial repair material is titanium mesh. This is a relatively traditional cranial repair material and has been used for a long time, 20 to 30 years. Compared to earlier materials, titanium mesh is advanced. However, there are still some defects and shortcomings of this kind of metal mesh material, such as postoperative infection, rejection, wear and tear of the scalp, resulting in the exposure of the material; titanium mesh insulation is not good, the patient’s sensitivity to the external environment of the hot and cold discomfort; titanium mesh metal material, which affects the patient to accept the postoperative CT, magnetic resonance examination; can not do the fine and complex shaping. Another important point is that the titanium mesh hardness is not too high, not strong enough, if the external force again, easy to cause the titanium mesh collapse deformation, and may even hurt the brain tissue, very dangerous. The current clinical new polymer PEEK material, the material is much stronger than titanium mesh. PEEK material is a new type of special polymer materials, the name of the chemical name called polyether ether ketone, its texture is very hard, low density, high strength, good protective properties. Moreover, PEEK material has excellent properties, such as histocompatibility, elasticity, heat conduction, hardness, stability, radiation transmittance, etc., which is comparable to the performance of autologous skull, and it can effectively avoid the problems that may arise from titanium mesh, and it has become the new trend of craniofacial repair materials. Our team not only uses this new material extensively, but also continuously improves and upgrades the technology and optimizes the design of the material, and introduces the concept of cosmetic plastic surgery, so as to carry out PEEK cranial bone repair and reconstructive surgery in a comprehensive way, and achieve the organic unity of anatomical integrity, perfect function, and beautiful appearance, which has been widely acclaimed.