Fibrous exudate is an exudate characterized by the presence of large amounts of cellulose. When fibrinitis occurs in the plasma membrane and lung, a small amount of fibrin exudate can be dissolved and absorbed; a large amount of fibrin exudate is prone to mechanization and even occlusion of the plasma membrane cavity, causing organ dysfunction. For example, in fibrinous pericarditis, the two layers of the dirty wall of the pericardium rub against each other due to the heart’s movement, so that the fibrin exuded in the pericardial cavity is in the shape of villi on the surface of the pericardium, which is called “villi heart”. If neutrophils exude less, the protein hydrolase released is relatively insufficient to completely dissolve and absorb the fibrin, which can be mechanized through the growth of granulation tissue and finally lead to fibrosis. How to effectively prevent fibrous exudate? The main principles are to keep the respiratory tract unobstructed, control infection, maintain water-electrolyte balance and prevent serious complications. 1. Keep the respiratory tract unobstructed: moisten the airway to facilitate the discharge of secretions. Provide oxygen in time, give nebulized inhalation to dilute sputum and aspirate it in time. Observe closely the changes of the disease and pay attention to the symptoms of airway obstruction, of which the monitoring of respiratory frequency and abnormal activity of auxiliary respiratory muscles is a basic measure. 2.Medication: Although antibiotics are ineffective in cases of viral infection, most of the heavier cases are combined with bacterial infection due to the rapid development of the disease. Generally, antibiotic treatment can be given including penicillin, erythromycin, aminoglycosides or cephalosporins. After the results of bacterial culture and drug sensitivity tests are available, then sensitive drugs are selected for treatment. The application of hormones is still controversial. Opponents believe that it is detrimental to the body’s production of antiviral antibodies and may cause the spread of viral infection. However, in recent years, most scholars believe that hormone therapy has obvious effects on reducing obstruction and avoiding tracheotomy. The theory is based on reducing inflammatory edema and preventing the destruction of epithelial cilia. Combined use of antibiotics and steroid hormone: can be used Pioneerin 5.0g plus dexamethasone 5-10mg intravenous drip, or penicillin plus hydrocortisone intravenous drip, in order to achieve the efficacy of infection control, anti-inflammatory and swelling. Ultrasonic nebulized inhalation of antibiotics and steroid hormones can be used. Use gentamicin 80,000 units plus dexamethasone 2mg, dilute with saline 20-50ml and then ultrasonic nebulized inhalation to achieve rapid reduction of laryngeal mucosal edema, secretion exudation reduction and relief of local symptoms. 3.Tracheotomy: If conservative treatment is ineffective and laryngeal obstruction is not relieved or significantly reduced, tracheotomy should be performed in a timely manner. It has been reported that in severe measles and influenza A virus epidemic combined with this disease, the proportion of patients requiring tracheotomy is relatively high. Postoperatively, saline, antibiotic or chymotrypsin solution is placed in the trachea every half hour and subsequently removed by aspiration. If scabs and fibrin-like pseudomembranes cannot be aspirated, they can be clamped out and aspirated by inserting bronchoscope through the tracheotomy opening. 4.Supportive treatment: including appropriate rehydration to maintain water and electrolyte balance and to avoid drying of endotracheal secretions. In addition, small amount of blood or plasma transfusion can be used to increase the resistance. Morphine and atropine are contraindicated during treatment. Antihistamines should also be used sparingly or not because they inhibit the secretion of respiratory glands and dry the mucous membrane and secretions, which can aggravate respiratory distress.