Stomach pain in the middle of the night after going to the toilet is no longer painful, may be physiological reasons, irritable bowel syndrome, intestinal inflammation and other causes. 1. Physiological reasons: may be due to too much spicy stimulating food or cold food, the gastrointestinal mucosa caused by certain stimulation, thus causing pain symptoms, after defecation symptoms will be relieved. 2. Irritable Bowel Syndrome (IBS): It is a common dysfunctional syndrome, which may be caused by nervousness, anxiety and other emotions, or may be caused by overwork, which often leads to abdominal pain or abdominal discomfort, and the symptoms will be relieved after defecation. 3. Intestinal inflammation: such as parasitic infection or bacterial infection, often also cause stomach pain, after defecation symptoms will be relieved. The pain in the stomach in the middle of the night after going to the toilet, there may be other causes, if the symptoms continue to be unrelieved, it is recommended to consult a doctor in a timely manner, under the guidance of a doctor to clarify the cause and targeted treatment, do not take medication, so as not to delay the condition.