After the hepatitis B vaccination, infants should pay attention to not touching the wound with water, taking the body temperature, observing whether there is fever and whether there is a rash in the area where the injection was given. If there is a large rash, it means that you are allergic to the vaccine and need to go to the hospital for further treatment. The hepatitis B vaccination requires three doses, which are given at birth, in the first month and in the sixth month of life. After the vaccination, a high concentration of hepatitis B surface antibody will be produced to protect against hepatitis B virus infection.