Anastrozole is an aromatase inhibitor, aromatase inhibitors will lead to bone calcium loss, patients with finger pain and morning stiffness of the fingers, and even large joint pain, consider anastrozole-induced low blood calcium levels or bone loss. Some patients with finger pain do not have a serious decrease in bone mineral density, the specific cause is not clear, the treatment can be taken daily sun exposure 1-2h, oral calcium can choose Calcium D, oral aminoglucose to protect the joint surfaces, so as to reduce morning stiffness and finger pain.