INH has a bactericidal effect on Mycobacterium tuberculosis both inside and outside macrophages. The dose for adults is 300mg/day, taken in a single dose; for children is 5-10mg/kg/day, the maximum dose should not exceed 300mg/day; the dose for tuberculous meningitis and hematogenous tuberculosis can be increased to 20-30mg/kg for children and 10-20mg/kg for adults. If peripheral neuritis occurs, vitamin B↓6 (pyridoxine) can be taken. 2, rifampicin: the minimum antibacterial concentration of 0.06-0.25μg/ml, has a rapid bactericidal effect on Mycobacterium tuberculosis inside and outside the macrophage, especially for the C flora has a unique sterilization effect. The dose for adults is 8-10mg/kg daily, 450mg for those weighing 50kg or less, 600mg for those weighing 50kg or more, taken in a single dose. For children, the daily dose is 10-20mg/kg, and the intermittent dose is 600-900mg, twice or three times a week. If transient aminotransferases rise after dosing, continue dosing and observe with hepatoprotective treatment, discontinue immediately if jaundice occurs. Influenza-like symptoms, skin syndrome, and thrombocytopenia mostly appear in intermittent therapy. It is contraindicated for those within 3 months of pregnancy and should be used with caution for those over 3 months. 3.Pyrazinamide: Pyrazinamide has a unique sterilization effect, mainly killing B flora in the acidic environment of macrophages. Adults use 1.5g/d, 3 times a week use 1.5~2.0g/d, children use 30~40mg/kg daily. common adverse reactions are hyperuricemia, liver damage, loss of appetite, arthralgia and nausea. 4. ethambutol: the minimum inhibitory concentration of ethambutol against Mycobacterium tuberculosis is 0.95~7.5μg/ml, easily absorbed orally, the adult dose is 0.75~1. 0g/d, 3 times weekly dose is 1.0~1.25g/d. Adverse effects are optic neuritis, visual acuity and visual field should be measured before treatment, closely observed during treatment, and patients should be reminded to seek medical attention when abnormal visual acuity is found. Given that children have no ability to judge symptoms, it is not used. 5, streptomycin: streptomycin has a bactericidal effect on Mycobacterium tuberculosis in the alkaline environment outside macrophages. Intramuscular injection, the daily amount of 0.75g, 5 times a week; intermittent dosing is 0.75-1.0g each time, 2-3 times a week. Adverse reactions are mainly ototoxicity, vestibular impairment and nephrotoxicity, etc. Strictly control the use of dose, children, the elderly, pregnant women, hearing impairment and renal dysfunction should be used with caution or not. Uniform standard chemotherapy regimen 1. Treatment regimen for primary treatment of Tu-Yang pulmonary tuberculosis including primary treatment of Tu-Yin with cavity formation or cornified pulmonary tuberculosis. (1) Daily drug regimen: Intensification period: isoniazid, rifampin, pyrazinamide and ethambutol, administered in a single dose for 2 months. Consolidation phase: isoniazid, rifampicin, dosed for 4 months. (2) Intermittent dosing regimen: Intensification phase: isoniazid, rifampin, pyrazinamide and ethambutol, every other day or 3 times a week for 2 months. Consolidation period: isoniazid and rifampin every other day or 3 times a week for 4 months. 2. Treatment regimen for retreatment of smear-positive tuberculosis (1) Daily drug regimen: Intensive phase: isoniazid, rifampin, pyrazinamide, streptomycin and ethambutol, once daily for 2 months. Consolidation phase: isoniazid, rifampin and ethambutol once daily for 4 to 6 months. If the sputum bacteria are not negative at 4 months of treatment during the consolidation period, the treatment period may be extended for another 2 months. (2) Intermittent dosing regimen: Intensive phase: isoniazid, rifampin, pyrazinamide, streptomycin and ethambutol once every other day or 3 times a week for 2 months. Consolidation phase: isoniazid, rifampin and ethambutol every other day or 3 times a week for 6 months. 3. Treatment regimen for primary smear-negative tuberculosis (1) Daily drug regimen: Intensification phase: isoniazid, rifampin, and pyrazinamide once daily for 2 months. Consolidation period: isoniazid, rifampicin, once daily for 4 months. (2) Intermittent dosing regimen: Intensification phase: isoniazid, rifampin, pyrazinamide, once every other day or 3 times a week for 2 months. Consolidation period: isoniazid, rifampin, once every other day or 3 times a week for 4 months.