How to regulate indigestion in newborns. First of all, be sure to pay attention to keep warm, the house must be kept fresh air, do not catch cold. If you have indigestion or indigestible stools or unformed stools, you can apply probiotics and digestive drugs, or lactase. Then you can give him some hot water, do not give him cold food, must pay attention to keep warm, because usually do not pay attention to keep warm, or cold, can cause indigestion.